Destin 456 Florida Panhandle vacation rentals

Florida Panhandle vacation rentals

Our incredible Florida Panhandle vacation rentals are the perfect way to experience the beauty and charm of this scenic region. From pristine beaches and crystal-clear waters to vibrant coastal towns and natural wonders, the Florida Panhandle has something for everyone.

Panhandle Florida vacation rentals with amazing amenities

Vacation rentals in Florida Panhandle come in a variety of options, including beachfront condos, spacious villas, and luxury homes. These rentals provide the comfort and convenience of a home away from home, with amenities such as fully equipped kitchens, private pools, outdoor grilling areas, and stunning views of the Gulf of Mexico. Luxurious in-home amenities complete the picture, with facilities including game rooms, home theaters, and pet friendly options available.

Whether you're planning a family vacation, a romantic getaway, or a fun-filled trip with friends, Florida Panhandle vacation rentals provide a comfortable and convenient base to explore this beautiful region. With its stunning beaches, coastal charm, and abundant outdoor activities, the Florida Panhandle offers an unforgettable vacation experience.

View of vacation homes on a white sand beach
Aerial shot of highway across the sea in Destin

Things to do

  • White sand beach in Florida at sunset
    The Florida Panhandle is renowned for its pristine, white sandy beaches and turquoise waters. From Destin to Pensacola Beach, visitors can enjoy sunbathing, swimming, and a range of water activities in a picturesque coastal setting.

  • Florida Capitol building in Tallahassee
    Tallahassee, the capital city of Florida, is a vibrant and diverse destination. It offers a mix of historic landmarks, cultural attractions, outdoor recreational opportunities, and a bustling college town atmosphere.

  • Mangrove swamp in Walluka Springs State park
    State parks
    Florida Panhandle state parks offer breathtaking natural beauty, pristine beaches, diverse wildlife, and recreational activities. Explore trails, swim, and enjoy outdoor adventures in parks like Grayton Beach, St. George Island, and Henderson Beach.

  • Stalagmites and stalactites in Florida underground caverns
    Florida caverns
    Florida Panhandle Caverns, such as Florida Caverns State Park, offer stunning underground formations and guided tours, providing a unique opportunity to explore the natural beauty and geological wonders of the region.

  • Fort Pickens historic building with stone arches on white sand
    Fort Pickens
    Fort Pickens is a historic coastal fort located on Santa Rosa Island in the Florida Panhandle. It offers picturesque beaches, camping opportunities, nature trails, and a glimpse into the region's military history.

  • A small fishing boat on still water in a mangrove
    Apalachicola National Forest
    Apalachicola National Forest, located in the Florida Panhandle, encompasses over 500,000 acres of diverse ecosystems. It offers opportunities for hiking, camping, fishing, and wildlife viewing in its beautiful forests, wetlands, and rivers.

  • A blue and yellow propellor on the wing of a plane
    National Naval Aviation Museum
    The National Naval Aviation Museum, located in Pensacola, Florida, showcases the history and technology of naval aviation. It features a vast collection of aircraft, exhibits, and interactive displays. Admission is free.

Luxury Vacation Rentals

A curated portfolio of the best vacation homes and villas in the world’s top destinations

Travel Planners

Experienced vacation rental and villa experts to help you find the perfect home

Concierge & Support

Enjoy 5-star hotel concierge services and dedicated local support with every stay

A chef prepares food for guests in one of our Spectrum vacation rentals

Florida Panhandle vacation packages with Travel Extras

Our Florida Panhandle vacation packages with Travel Extras take your stay to the next level. With fully customizable extras including private chefs, attraction tickets, airport transfers, grocery deliveries, and more, you can tailor your stay to your wishes and requirements.

Our Travel Planner team is on hand from the moment you book to answer questions, arrange Travel Extras, and generally make your Florida Panhandle vacation utterly unforgettable.

Seacrest 3 pet friendly vacation rentals Florida Panhandle

Pet friendly vacation rentals Florida Panhandle

We offer a fantastic range of pet friendly vacation rentals in Florida Panhandle, ensuring that your four-legged friends can join you on your coastal getaway. From charming beach villas to spacious condos, these accommodations cater to both you and your pets. Many rentals provide amenities such as fenced yards, and are close to pet-friendly beaches, and nearby walking trails.

With pet-friendly vacation rentals in the Florida Panhandle, you can create unforgettable memories with your four-legged companions while enjoying the beautiful beaches and outdoor activities of the region.

Book with Confidence

With over 100,000 happy guests every year, you can book your next stay with us with total confidence.

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Seacrest Beach 4 florida panhandle condo rentals

Florida Panhandle condo rentals

Stay in total luxury in our fabulous Florida Panhandle condo rentals, providing comfortable and convenient stays in the region's most beautiful destinations. These condos are located in popular beach locations such as Destin, Panama City Beach, and Pensacola Beach, offering easy access to the stunning Gulf Coast.

Whether you're traveling as a couple, with family, or in a group, you'll find condos of various sizes and styles to suit your needs. Many of these rentals are located in beachfront or waterfront complexes, offering breathtaking views and direct access to the beach. Our Florida Panhandle condos also feature amenities like pools, game rooms, and home theaters.

Dune Allen Beach 5 view of beach with vacation rentals along the sand

Florida Panhandle oceanfront vacation rentals

Florida Panhandle oceanfront vacation rentals offer the perfect opportunity to enjoy the stunning beaches and breathtaking views of the Gulf of Mexico. These villas, condos, and vacation homes are located directly on the coastline, allowing you to step out of your accommodation and onto the sandy shores.

Oceanfront vacation rentals are fantastic for the best family vacation in Florida Panhandle, and feature private balconies or patios that overlook the beach, providing an ideal setting for enjoying sunsets or sipping your morning coffee while listening to the sound of crashing waves. Our Florida Panhandle oceanfront vacation rentals also offer amenities like private pools, beach access, BBQ grills, and outdoor seating areas.